Japan Bio Science Laboratories (JBSL) was founded in 1974, specializes in the development and manufacturing of functional health supplement and food ingredients anchored by the corporate belief of “the harmony of human beings and Mother Nature.” JBSL currently manufactures and markets NSK-SD®, ChalCurb® Ashitaba Leaf Powder, Sesame Minerals and Biozyme, from its plants in Japan. From its world corporate headquarters in Osaka, Japan, JBSL continues to invest in technology, research and development to provide safe and effective health ingredients that address modern health concerns.

JBSL’s first product Biozyme is a fermented vegetable extract and postbiotic produced using a fermentation process with 40 different vegetables and herbs. In 1998, JBSL was the first company to commercialize nattokinase, an enzyme rich in cardiovascular benefits that is derived from the Japan fermented soybean dish natto. JBSL’s brand of nattokinase, NSK-SD®, is the original and authentic nattokinase distributed by JBSL-USA. It is the only nattokinase with published identity, safety, and efficacy studies. Now celebrating its 50th anniversary, JBSL has renewed its company mission statement to ''Through Science, Creating a Healthier World'', and achieves this by offering a range of raw materials derived from natural ingredients backed by safety and efficacy studies.

JBSL-USA is the US office of JBSL and is based in Walnut Creek, CA. JBSL-USA helps to serve all countries in the Americas as well as Europe.